SEM of a stage 2, 4-cell embryo in vitro, (original magnification x1300). The zona pellucida (ZP) has a spongy appearance with one corona radiata cell (C) attached. Arrow points to the hole in the zona pellucida resulting from the intracytoplasmic sperm injection procedure.
From: Makabe et al., 2001. Reproduced with permission of the Italian Journal of Anatomy and Embryology.
Keywords: corona radiata cell(s), four-cell embryo, stage 2 embryo, zona pellucida
Source: The Virtual Human Embryo.