By approximately 2 1/2 weeks,
the epiblast has formed
3 specialized tissues,
or germ layers,
called ectoderm,
endoderm,
and mesoderm.
Ectoderm gives rise
to numerous structures
including the brain,
spinal cord,
nerves,
skin,
nails,
and hair.
Endoderm produces the lining
of the respiratory system
and digestive tract,
and generates
portions of major organs
such as the liver
and pancreas.
Mesoderm forms the heart,
kidneys,
bones,
cartilage,
muscles,
blood cells,
and other structures.